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Jong-Koo Kang Selected Research

1-O-hexyl-2,3,5-trimethylhydroquinone

5/2018HX-1171 attenuates pancreatic β-cell apoptosis and hyperglycemia-mediated oxidative stress via Nrf2 activation in streptozotocin-induced diabetic model.
10/2017HX-1171, a Novel Nrf2 Activator, Induces NQO1 and HMOX1 Expression.
1/2015Single and multiple dose pharmacokinetics and tolerability of HX-1171, a novel antioxidant, in healthy volunteers.
9/2010Inhibitory Effect of 1-O-Hexyl-2,3,5-Trimethylhydroquinone on Dimethylnitrosamine-induced Liver Fibrosis in Male SD Rats.

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Jong-Koo Kang Research Topics

Disease

5Body Weight (Weight, Body)
06/2022 - 08/2004
4Neoplasms (Cancer)
10/2017 - 07/2005
3Liver Cirrhosis (Hepatic Cirrhosis)
10/2017 - 02/2010
3Seizures (Absence Seizure)
07/2008 - 01/2002
3Brain Injuries (Brain Injury)
07/2007 - 01/2002
2Necrosis
06/2022 - 02/2010
2Fibrosis (Cirrhosis)
01/2015 - 09/2010
2Dementia (Dementias)
12/2012 - 01/2012
2Alzheimer Disease (Alzheimer's Disease)
12/2012 - 01/2012
2Vomiting
11/2005 - 07/2005
2Poisoning
11/2005 - 01/2002
1Hypertrophy
06/2022
1Hyperglycemia
05/2018
1Rheumatoid Arthritis
11/2017
1Experimental Arthritis
11/2017
1Parkinson Disease (Parkinson's Disease)
09/2014
1Leukemia
11/2012
1Lymphoma (Lymphomas)
11/2012
1Melanoma (Melanoma, Malignant)
11/2012
1Multiple Myeloma
11/2012
1Teratogenesis
11/2012
1Renal Cell Carcinoma (Grawitz Tumor)
11/2012
1Hypoxia (Hypoxemia)
11/2012
1Memory Disorders (Memory Loss)
01/2012
1Inflammation (Inflammations)
02/2010
1Cerebral Infarction
07/2007
1Thromboembolism
07/2007
1Thrombosis (Thrombus)
07/2007
1Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)
07/2007
1Diarrhea
11/2005
1Tremor (Tremors)
11/2005
1Pica (Geophagia)
07/2005
1Hyperplasia
08/2004
1Organophosphate Poisoning
01/2002

Drug/Important Bio-Agent (IBA)

41-O-hexyl-2,3,5-trimethylhydroquinoneIBA
05/2018 - 09/2010
3SomanIBA
07/2008 - 01/2002
2AntioxidantsIBA
01/2015 - 02/2010
2Amyloid Precursor Protein Secretases (beta-Secretase)IBA
12/2012 - 01/2012
2Messenger RNA (mRNA)IBA
11/2012 - 09/2010
2Dimethylnitrosamine (Nitrosodimethylamine)IBA
09/2010 - 02/2010
2Neuroprotective AgentsIBA
07/2007 - 01/2002
2asoxime chloride (H16)IBA
11/2005 - 01/2002
2Procyclidine (Procyclidine Hydrochloride)FDA Link
11/2005 - 01/2002
2AtropineFDA LinkGeneric
11/2005 - 01/2002
2PhysostigmineIBA
11/2005 - 01/2002
1PowdersIBA
06/2022
1Aspartate Aminotransferases (Aspartate Transaminase)IBA
06/2022
1Alanine Transaminase (SGPT)IBA
06/2022
1Streptozocin (Streptozotocin)FDA Link
05/2018
1Methotrexate (Mexate)FDA LinkGeneric
11/2017
1Interleukin-6 (Interleukin 6)IBA
11/2017
1AutoantigensIBA
11/2017
1Infliximab (Remicade)FDA Link
11/2017
1Vitamin EFDA LinkGeneric
10/2017
1Free RadicalsIBA
09/2014
1Pharmaceutical PreparationsIBA
02/2014
1Ethanol (Ethyl Alcohol)IBA
12/2012
1Amyloid beta-PeptidesIBA
12/2012
1Superoxide DismutaseIBA
11/2012
1ManganeseIBA
11/2012
1Glutathione PeroxidaseIBA
11/2012
1Caspase 3 (Caspase-3)IBA
11/2012
1NicotineFDA Link
11/2012
1ResveratrolIBA
11/2012
1Interleukin-2 (IL2)IBA
11/2012
1Sirtuin 1IBA
11/2012
1Phospholipid Hydroperoxide Glutathione PeroxidaseIBA
11/2012
1Amyloid (Amyloid Fibrils)IBA
01/2012
14-O-methylhonokiolIBA
01/2012
1Transforming Growth Factors (Transforming Growth Factor)IBA
09/2010
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
09/2010
1Transforming Growth Factor beta (TGF-beta)IBA
02/2010
1CytokinesIBA
02/2010
1CoffeeFDA Link
02/2010
1Evans Blue (Blue, Evans)FDA Link
07/2008
1triphenyltetrazoliumIBA
07/2007
1PEG-hemoglobinIBA
07/2007
1Cholinergic Agents (Cholinergics)IBA
11/2005
1Nerve AgentsIBA
11/2005
1Serotonin (5 Hydroxytryptamine)IBA
07/2005
1AntiemeticsIBA
07/2005
1Antineoplastic Agents (Antineoplastics)IBA
07/2005
1KaolinIBA
07/2005
1Tropisetron (Navoban)IBA
07/2005
1GenisteinIBA
08/2004
1Estradiol (Delestrogen)FDA LinkGeneric
08/2004
1Anticonvulsants (Antiepileptic Drugs)IBA
01/2002

Therapy/Procedure

2Therapeutics
11/2017 - 11/2012
2Transdermal Patch
11/2005 - 07/2005
1East Asian Traditional Medicine (Oriental Medicine)
02/2014
1Intraperitoneal Injections
09/2010
1Cesarean Section (Caesarean Section)
03/2010
1Intra-Arterial Infusions
07/2007
1Subcutaneous Injections
11/2005